The effect of 6 days of sodium phosphate supplementation on appetite, energy intake, and aerobic capacity in trained men and women

Int J Sport Nutr Exerc Metab. 2012 Dec;22(6):422-9. doi: 10.1123/ijsnem.22.6.422. Epub 2012 Jul 4.

Abstract

Ingestion of an acute dose of phosphate has been shown to attenuate energy intake in the subsequent meal. This raises the question of whether the practice of phosphate supplementation over a number of days by athletes to enhance performance also influences energy intake. This study investigated the effect of 6 d of phosphate supplementation on appetite and energy intake, as well as aerobic capacity, in trained individuals. Twenty participants completed two 6-d phases of supplementation with either sodium phosphate (50 mg/kg of fat-free mass per day) or a placebo in a double-blinded, counterbalanced design. On Days 1, 2, and 6 of supplementation, a laboratory meal was provided to assess appetite and ad libitum energy intake. All other food and drink consumed during each supplementation phase were recorded in a food diary. After the 6 d of supplementation, peak aerobic capacity (VO(2peak)) was assessed. There was no difference in energy intake at the laboratory meal after an acute dose (i.e., on Day 1; placebo 2,471 ± 919 kJ, phosphate 2,353 ± 987 kJ; p = .385) or prolonged supplementation with sodium phosphate (p = .581) compared with placebo. Likewise, there was no difference in VO(2peak) with phosphate supplementation (placebo 52.6 ± 5.2 ml · kg(-1) · min(-1), phosphate 53.3 ± 6.1 ml · kg(-1) · min(-1); p = .483). In summary, 6 d of sodium phosphate supplementation does not appear to influence energy intake. Therefore, athletes supplementing with sodium phosphate can do so without hindering their nutritional status. However, given that phosphate supplementation failed to improve aerobic capacity, the ergogenic benefit of this supplement remains questionable.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Appetite Regulation*
  • Appetite Stimulants / adverse effects
  • Appetite Stimulants / therapeutic use
  • Athletes
  • Body Mass Index
  • Dietary Supplements* / adverse effects
  • Double-Blind Method
  • Energy Intake*
  • Exercise*
  • Female
  • Humans
  • Male
  • Overweight / blood
  • Overweight / prevention & control*
  • Oxygen Consumption
  • Performance-Enhancing Substances / adverse effects
  • Performance-Enhancing Substances / therapeutic use
  • Phosphates / adverse effects
  • Phosphates / blood
  • Phosphates / therapeutic use*
  • Phosphorus / blood
  • Physical Fitness
  • Sports Nutritional Physiological Phenomena*
  • Western Australia
  • Young Adult

Substances

  • Appetite Stimulants
  • Performance-Enhancing Substances
  • Phosphates
  • Phosphorus
  • sodium phosphate