The reliability and validity of the mini-mental state examination in the elderly Croatian population

Dement Geriatr Cogn Disord. 2012;33(6):385-92. doi: 10.1159/000339596. Epub 2012 Jul 17.


Aim: The aim of this study was standardization and validation of the Mini-Mental State Examination (MMSE) in the general Croatian aging population.

Methods: Three-hundred and forty-four participants underwent the MMSE test, 217 cognitively healthy subjects without neurological and psychiatric disorders and 127 patients with mild cognitive impairment (MCI) or dementia.

Results: The optimal cutoff point for screening of the general Croatian population (cognitively healthy vs. MCI and dementia) is 26/27; in the Croatian population aged ≥65 years, the cutoff point is 24/25, whereas for screening of highly educated persons (≥14 years of education) aged ≥65 years a higher cutoff point should be used (26/27).

Conclusions: MMSE results when standardized and validated in a certain population might better contribute to recognition of the individuals at risk that should be directed to dementia outpatient clinics.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Aged
  • Alzheimer Disease / diagnosis
  • Case-Control Studies
  • Cognitive Dysfunction / diagnosis*
  • Croatia
  • Dementia / diagnosis*
  • Educational Status
  • Female
  • Humans
  • Male
  • Mass Screening
  • Mental Status Schedule / statistics & numerical data*
  • Middle Aged
  • Psychometrics / instrumentation
  • Reproducibility of Results