Sporoptosis: sowing the seeds of nuclear destruction

Dev Cell. 2012 Jul 17;23(1):5-6. doi: 10.1016/j.devcel.2012.06.016.


What are the origins of programmed cell death (PCD)? In this issue of Developmental Cell, Eastwood et al. (2012) uncover an ancient developmental program of nuclear destruction in yeast, implying that some PCD mechanisms could have emerged from nonlethal processes before the divergence of fungi and metazoan.

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