Metastatic melanoma to the heart

Curr Probl Diagn Radiol. 2012 Sep-Oct;41(5):159-64. doi: 10.1067/j.cpradiol.2011.09.001.

Abstract

Melanoma is a common neoplasm with a propensity to metastasize to the heart. Although cardiac metastasis is rarely diagnosed ante mortem, using a multimodality approach, several imaging findings may be seen. Echocardiography is often the initial imaging method used to detect cardiac metastases and their complications. On computed tomography, intraluminal filling defects and myocardial/pericardial nodules may be seen. On magnetic resonance imaging, metastatic melanoma is classically hyperintense on T1 images and hypointense on T2 images, a result of the T1 shortening of melanin; however, this is seen in a minority of cases. As melanoma metastases are fluorine-18-fluorodeoxyglucose avid, fluorine-18-fluorodeoxyglucose positron emission tomography may also be used to detect cardiac metastases.

Publication types

  • Review

MeSH terms

  • Echocardiography / methods
  • Fluorodeoxyglucose F18
  • Heart / diagnostic imaging
  • Heart Neoplasms / diagnosis*
  • Heart Neoplasms / secondary*
  • Humans
  • Magnetic Resonance Imaging / methods
  • Melanoma / diagnosis*
  • Melanoma / secondary*
  • Myocardium / pathology
  • Positron-Emission Tomography / methods
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed / methods

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18