A prospective, randomized, single-blinded trial on the effect of early rehabilitation on daily activities and motor function of patients with hemorrhagic stroke

J Clin Neurosci. 2012 Oct;19(10):1376-9. doi: 10.1016/j.jocn.2011.10.021. Epub 2012 Jul 18.


To investigate whether early rehabilitation has a positive impact on the recovery of the activities of daily living and motor function after intracerebral hemorrhagic stroke, 364 patients with hemorrhagic stroke were selected and randomly divided into a rehabilitation group and a control group. The rehabilitation group underwent a standardized, three-stage rehabilitation program. The control group was treated with standard hospital ward, internal medical intervention. The simplified Fugl-Myere assessment scale (FMA) and Modified Barthel Index (MBI) were administered at various time points. The magnitude of improvement was significantly higher in the rehabilitation group than in the control group for both the FMA (p<0.05) and MBI scores (p<0.05). The greatest improvement was observed in the first month post-stroke. Thus, our study shows that early rehabilitation can significantly improve the daily activities and motor functions of patients with stroke.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living*
  • Aged
  • Female
  • Glasgow Coma Scale
  • Humans
  • Intracranial Hemorrhages / complications*
  • Intracranial Hemorrhages / rehabilitation
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Motor Activity / physiology*
  • Occupational Therapy / methods*
  • Physical Therapy Modalities*
  • Prospective Studies
  • Recovery of Function
  • Retrospective Studies
  • Single-Blind Method
  • Stroke Rehabilitation
  • Stroke* / etiology
  • Stroke* / psychology
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome