Disease activity assessment and patient-reported outcomes in patients with early rheumatoid arthritis

Rheum Dis Clin North Am. 2012 May;38(2):299-310. doi: 10.1016/j.rdc.2012.04.005. Epub 2012 May 25.


Quantitative assessment of disease activity and patient-reported outcomes are recognized as valuable in the management of rheumatoid arthritis (RA). Complexities of assessment of RA include challenges concerning measures themselves, as a gold standard measure for disease status does not exist. This article discusses the hurdles in the implementation of quantitative assessment of RA in usual clinical care and also provides an example to monitor patients with early RA.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / diagnosis*
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / physiopathology
  • Disease Progression
  • Drug Delivery Systems
  • Early Diagnosis
  • Health Status
  • Humans
  • Joints / pathology
  • Joints / physiopathology
  • Outcome Assessment, Health Care / methods*
  • Prognosis
  • Self Report*


  • Antirheumatic Agents