Plant hormonal regulation of nitrogen-fixing nodule organogenesis

Mol Cells. 2012 Aug;34(2):117-26. doi: 10.1007/s10059-012-0131-1. Epub 2012 Jul 20.


Legumes have evolved symbiotic interactions with rhizobial bacteria to efficiently utilize nitrogen. Recent progress in symbiosis has revealed several key components of host plants required for nitrogen-fixing nodule organogenesis, in which complicated metabolic and signaling pathways in the host plant are reprogrammed to generate nodules in the cortex upon perception of the rhizobial Nod factor. Following the recognition of Nod factors, plant hormones are likely to be essential throughout nodule organogenesis for integration of developmental and environmental signaling cues into nodule development. Here, we review the molecular events involved in plant hormonal regulation and signaling cross-talk for nitrogen-fixing nodule development, and discuss how these signaling networks are integrated into Nod factor-mediated signaling during plant-microbe interactions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Fabaceae / genetics
  • Fabaceae / metabolism*
  • Gene Expression Regulation, Plant
  • Genes, Plant
  • Nitrogen Fixation / genetics
  • Nitrogen Fixation / physiology*
  • Plant Growth Regulators / genetics
  • Plant Growth Regulators / metabolism*
  • Plant Physiological Phenomena
  • Plant Proteins / genetics
  • Plant Proteins / metabolism*
  • Plants / genetics
  • Plants / metabolism*
  • Plants, Genetically Modified
  • Signal Transduction


  • Plant Growth Regulators
  • Plant Proteins