A prospective series of patients with chronic Achilles tendinopathy treated with autologous-conditioned plasma injections combined with exercise and therapeutic ultrasonography

J Foot Ankle Surg. Nov-Dec 2012;51(6):706-10. doi: 10.1053/j.jfas.2012.06.009. Epub 2012 Jul 21.

Abstract

Chronic Achilles tendinopathy is a difficult problem to manage, because it can result in significant patient morbidity. We conducted a prospective case series involving 26 patients (2 bilateral cases) with painful and ultrasound-confirmed Achilles tendinopathy for a minimum duration of 6 months. Our objective was to assess whether this condition can be effectively treated with a treatment protocol combining an intratendinous autologous-conditioned plasma injection followed by a standardized rehabilitation protocol. The rehabilitation protocol consisted of full weightbearing in a pneumatic cast boot for 6 weeks, therapeutic ultrasound treatment, and an eccentric exercise program. Our results showed statistically significant improvements in terms of pain (p < .0001), other symptoms (p = .0003), activities of daily living (p = .0002), sports activities (p = .0001), and quality of life (p = .0002). We believe that the use of autologous-conditioned plasma can provide a potential treatment solution for chronic Achilles tendinopathy.

MeSH terms

  • Achilles Tendon
  • Activities of Daily Living
  • Adult
  • Chronic Disease
  • Clinical Protocols
  • Exercise Therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Platelet-Rich Plasma*
  • Prospective Studies
  • Quality of Life
  • Tendinopathy / rehabilitation*
  • Ultrasonic Therapy