The genetic epidemiology of nonalcoholic fatty liver disease: toward a personalized medicine

Clin Liver Dis. 2012 Aug;16(3):467-85. doi: 10.1016/j.cld.2012.05.011. Epub 2012 Jun 20.

Abstract

The understanding of the genetic bases of complex diseases such as nonalcoholic fatty liver disease opens new opportunities and challenges. This article explores new tools designed toward moving genomic data into clinical medicine, providing putative answers to more practical questions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Epigenomics / methods
  • Epigenomics / statistics & numerical data
  • Fatty Liver / epidemiology*
  • Fatty Liver / genetics*
  • Female
  • Genetic Loci
  • Genetic Predisposition to Disease
  • Genetic Variation
  • Genome-Wide Association Study / statistics & numerical data
  • Humans
  • Lipase / genetics
  • Male
  • Membrane Proteins / genetics
  • Molecular Epidemiology
  • Non-alcoholic Fatty Liver Disease
  • Precision Medicine*
  • Sequence Analysis, DNA / methods
  • Sex Factors

Substances

  • Membrane Proteins
  • Lipase
  • adiponutrin, human