Whole-body diffusion-weighted MRI: tips, tricks, and pitfalls

AJR Am J Roentgenol. 2012 Aug;199(2):252-62. doi: 10.2214/AJR.11.7866.


Objective: We examine the clinical impetus for whole-body diffusion-weighted MRI and discuss how to implement the technique with clinical MRI systems. We include practical tips and tricks to optimize image quality and reduce artifacts. The interpretative pitfalls are enumerated, and potential challenges are highlighted.

Conclusion: Whole-body diffusion-weighted MRI can be used for tumor staging and assessment of treatment response. Meticulous technique and knowledge of potential interpretive pitfalls will help to avoid mistakes and establish this modality in radiologic practice.

Publication types

  • Review

MeSH terms

  • Artifacts
  • Contrast Media
  • Diagnosis, Differential
  • Diffusion Magnetic Resonance Imaging / instrumentation
  • Diffusion Magnetic Resonance Imaging / methods*
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods
  • Neoplasms / diagnosis*
  • Neoplasms / therapy*
  • Whole Body Imaging*


  • Contrast Media