Adrenal extramedullary hematopoiesis associated with β-thalassemia major

Hematol Rep. 2012 May 10;4(2):e7. doi: 10.4081/hr.2012.e7. Epub 2012 Apr 13.

Abstract

The presence of apparently normal hematopoietic tissue outside of bone marrow cavity is defined as extramedullary hematopoiesis (EMH). EMH is a rare complication in thalassemia major (TM) and adrenal gland as well. This report describes a case of adrenal EMH in a 26-year-old man with β-TM. He has been transfused with regular blood transfusion since 9 months. During the routine physical examination he was incidentally found to have a hypoechoic mass at his abdominal ultrasonography. Abdominal computed tomography scan revealed a right well-defined suprarenal mass 7.7×7.3×5.8 cm in size. The diagnosis of EMH was confirmed with ultrasonographic-guided fine needle biopsy. Treatment options which include intensified regular blood transfusion and hydroxyurea have been started.

Keywords: adrenal gland.; extramedullary hematopoiesis; thalassemia major.

Publication types

  • Case Reports