Synthesis of Fischer Type-Carbene Complexes Containing a Coordinated Thioimidate Structural Motif

Dalton Trans. 2012 Sep 21;41(35):10568-75. doi: 10.1039/c2dt31297b. Epub 2012 Jul 25.


This paper describes a tandem strategy to synthesize a series of new Fischer carbene complexes [(CO)(4)M=C[N-(CH(2))(4)-]CH=C(NRR')(SR'); M = Cr, W; R = Ar, R' = Me, -(CH(2))(2)-] with a thioimide or thiazoline fragment, in which the sulfur or nitrogen atom is coordinated to a metal center, depending on the nature of alkylating groups included as R'. We have trapped by protonation the proposed intermediate as the thioamide 12 [(CO)(5)W=[N-(CH(2))(4)-]CH(2)C(S)NHPh], which reveals the pathway of this reaction.