Complete genome sequence of the hyperthermophilic archaeon Pyrococcus sp. strain ST04, isolated from a deep-sea hydrothermal sulfide chimney on the Juan de Fuca Ridge

J Bacteriol. 2012 Aug;194(16):4434-5. doi: 10.1128/JB.00824-12.


Pyrococcus sp. strain ST04 is a hyperthermophilic, anaerobic, and heterotrophic archaeon isolated from a deep-sea hydrothermal sulfide chimney on the Endeavour Segment of the Juan de Fuca Ridge in the northeastern Pacific Ocean. To further understand the distinct characteristics of this archaeon at the genome level (polysaccharide utilization at high temperature and ATP generation by a Na(+) gradient), the genome of strain ST04 was completely sequenced and analyzed. Here, we present the complete genome sequence analysis results of Pyrococcus sp. ST04 and report the major findings from the genome annotation, with a focus on its saccharolytic and metabolite production potential.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Anaerobiosis
  • DNA, Archaeal / chemistry*
  • DNA, Archaeal / genetics*
  • Genome, Archaeal*
  • Heterotrophic Processes
  • Hydrothermal Vents / microbiology*
  • Molecular Sequence Data
  • Pacific Ocean
  • Polysaccharides / metabolism
  • Pyrococcus / genetics*
  • Pyrococcus / isolation & purification
  • Pyrococcus / physiology
  • Seawater / microbiology
  • Sequence Analysis, DNA*
  • Sodium Chloride / metabolism
  • Sulfides / metabolism


  • DNA, Archaeal
  • Polysaccharides
  • Sulfides
  • Sodium Chloride
  • Adenosine Triphosphate

Associated data

  • GENBANK/CP003534