Lentigo maligna

Actas Dermosifiliogr. 2013 Nov;104(9):757-75. doi: 10.1016/j.ad.2012.05.006. Epub 2012 Jul 31.
[Article in English, Spanish]


Lentigo maligna is a type of in situ melanoma. It develops mainly in middle-aged and elderly individuals on areas of the skin chronically exposed to sunlight. It progresses to its invasive form, lentigo maligna melanoma, in 5% to 50% of cases. Management of lentigo maligna is open to debate, with a notable lack of randomized trials and specific guidelines and protocols. Early diagnosis and treatment is necessary to achieve cure if possible and prevent progression to invasive melanoma with the corresponding risk of metastasis. The treatment of choice for lentigo maligna is surgery. When surgery is not possible, other alternatives are available although outcomes and rates of recurrence are variable. The objective of this study was to review the diagnostic methods and criteria for lentigo maligna, as well as the different surgical options and alternatives to surgery, in order to provide information on the best approach in each case.

Keywords: Diagnosis; Diagnóstico; Lentigo maligna; Lentigo maligno; Tratamiento; Treatment.

Publication types

  • Review

MeSH terms

  • Humans
  • Hutchinson's Melanotic Freckle* / pathology
  • Hutchinson's Melanotic Freckle* / therapy
  • Skin Neoplasms* / pathology
  • Skin Neoplasms* / therapy