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Review
. 2012 Oct;23(10):1617-30.
doi: 10.1681/ASN.2012010058. Epub 2012 Aug 2.

Treatment of idiopathic membranous nephropathy

Meryl Waldman  1 , Howard A Austin 3rd
Affiliations
Review

Treatment of idiopathic membranous nephropathy

Meryl Waldman et al. J Am Soc Nephrol. 2012 Oct.

Abstract

Exciting progress recently has been made in our understanding of idiopathic membranous nephropathy, as well as treatment of this disease. Here, we review important advances regarding the pathogenesis of membranous nephropathy. We will also review the current approach to treatment and its limitations and will highlight new therapies that are currently being explored for this disease including Rituximab, mycophenolate mofetil, and adrenocorticotropic hormone, with an emphasis on results of the most recent clinical trials.

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Figures

Figure 1.
Figure 1.
Current consensus guidelines for treatment of IMN, adapted from Cattran et al. Possible positions of MMF and rituximab in treatment scheme based on available data (but not currently in guidelines). SAE, severe adverse event.
See this image and copyright information in PMC

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