The influences of natural zeolite (cliptinolite) on ammonia and biogenic amine formation by foodborne pathogen

J Food Sci. 2012 Aug;77(8):M452-7. doi: 10.1111/j.1750-3841.2012.02822.x.


The influence of natural zeolite on biogenic amines (BAs) and ammonia (AMN) production by eight common gram negative and positive foodborne pathogens (FBP) were investigated in histidine decarboxylase broth (HDB). Presence of 1% zeolite in the HDB resulted in significantly higher AMN production. Histamine (HIS) production by gram positive bacteria was as low as 0.5 mg/L, whereas Escherichia coli produced 18.96 mg/L of HIS. The use of zeolite also significantly suppressed HIS accumulation by E. coli, Pseudomonas aeruginosa, S. paratyphi A (P < 0.05), although zeolite addition stimulated HIS production by K. pneumonia and Aeromonas hydrophila. The range of tyramine (TYR) production by gram positive bacteria was 1.19 and 4.06 mg/L for Enteroccus faecalis and Listeria monocytogenes respectively. The results of study showed that the effect of zeolite on BAs and AMN production was dependent on bacterial strains, as well as zeolite concentrations used.

Practical application: Natural zeolites are the main absorptive, low-cost material used in agriculture and industry. Although the effect of zeolite on ammonia formation in some industrial systems is well known, there is limited information regarding the impact of zeolite on biogenic amine (BA) production by foodborne pathogens. The data presented in this article will help us to understand the impact of natural zeolite on BA and ammonia production by eight common foodborne pathogens.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ammonia / metabolism*
  • Biogenic Amines / biosynthesis*
  • Culture Media / chemistry
  • Enterococcus faecalis / drug effects
  • Enterococcus faecalis / metabolism
  • Escherichia coli / drug effects
  • Escherichia coli / metabolism
  • Food Contamination*
  • Food Microbiology*
  • Food Preservation
  • Histamine / biosynthesis
  • Histidine Decarboxylase / metabolism
  • Listeria monocytogenes / drug effects
  • Listeria monocytogenes / metabolism
  • Pseudomonas aeruginosa / drug effects
  • Pseudomonas aeruginosa / metabolism
  • Salmonella paratyphi A / drug effects
  • Salmonella paratyphi A / metabolism
  • Tyramine / biosynthesis
  • Zeolites / pharmacology*


  • Biogenic Amines
  • Culture Media
  • Zeolites
  • Ammonia
  • Histamine
  • Histidine Decarboxylase
  • Tyramine