Final report of the Cosmetic Ingredient Review Expert Panel on the safety assessment of methyl acetate

Int J Toxicol. 2012 Jul-Aug;31(4 Suppl):112S-36S. doi: 10.1177/1091581812444142.


Alkyl acetates, as well as acetic acid and acetate salts, are widely used cosmetic ingredients, with a wide range of functions as fragrances, solvents, or skin-conditioning agents, depending on the specific ingredient. Available data on alkyl acetates, and acetic acid and the alcohol to which they could be metabolized, were considered adequate to support the safety of the entire group in the present practices of use and concentration in cosmetics.

Publication types

  • Technical Report

MeSH terms

  • Acetates / adverse effects*
  • Acetates / pharmacokinetics
  • Animals
  • Cosmetics*
  • Female
  • Humans
  • Male
  • Risk Assessment


  • Acetates
  • Cosmetics
  • methyl acetate