Splenosis after splenectomy and spleen tissue autoimplantation: Late followup study

J Indian Assoc Pediatr Surg. 2012 Jul;17(3):104-6. doi: 10.4103/0971-9261.98120.

Abstract

Aim: In children suffering from severe hepatosplenic schistosomiasis, the surgical protocol includes splenectomy and autoimplantation of spleen morsels in the major omentum, which has the potential of reducing the overwhelming postsplenectomy infection (OPSI). The purpose of the study was to evaluate the remaining splenosis, with the mean postoperative followup of 12.1 ± 5.6 years; to compare the efficacy of the 2 evaluation tools.

Materials and methods: Nineteen patients underwent, when they were children, portal decompression and autoimplantation of spleen. After a mean age of 23.4 ± 5.3 years, they were investigated regarding the number of infections and OPSI. They had undergone hepatosplenic scintigraphy with labeled colloidal SnTc(99m) and abdominal ultrasound. It was considered efficient splenosis when the patients presented with 5 or more spleen nodules. The evaluation was performed by 3 observers.

Results: None of the patients had increased infection rate or developed OPSI. Sixteen (84.2%) presented efficient splenosis.

Conclusions: The remaining postoperative splenosis was considered efficient in the majority of patients in the long-term followup; and nuclear medicine was considered the gold standard for splenosis evaluation.

Keywords: Hepatosplenic schistosomiasis mansoni; over-whelming postsplenectomy infection; splenectomy; splenosis.