The present paper reports the results of a project aimed at providing Iran with a an online registry for breast cancer patients. A new ad hoc system/software has been developed in order to collect patients' data from the first visit to follow-up visits, including tests and Herceptin based therapy. The system has been designed to address both healthcare personnel needs, but also decision makers' information needs. After having identified in the country the laboratories performing the specific tests and the pharmacies that distribute Hercepting, the developed software have been installed in order to build the operational network representing the input points for the register. In 8 months of usage the results are: • Total number of Patients: 2240 inhabitant • Total number of doctors have participated in the program: 229 persons • Number of provinces contributing to the project: 17 provinces out of 30. Online registry of breast cancer is country's requirement because this system not only delivers services for laboratories, pharmacies and all physicians for their patients' follow up and monitoring, but also provides ability to access and analyze collected data for managers and experts.