Magnetic resonance imaging in the malformative syndromes with mental retardation

Pediatr Radiol. 1990;21(1):16-9. doi: 10.1007/BF02010806.


We reported on thirteen children affected with malformative syndromes associated with mental retardation. MRI examination showed in all of them different types of anomalies; agenesis of corpus callosum, ventricular dilatation and cerebral matter alterations were the most frequent findings. The authors give a brief description of the clinical reports and of the anomalies observed with MRI; they conclude that MRI seems to be a valuable tool especially for the study of the alterations of the cerebral matter and their correlation with mental retardation.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple* / pathology
  • Acrocephalosyndactylia / pathology
  • Adolescent
  • Agenesis of Corpus Callosum
  • Arnold-Chiari Malformation / pathology
  • Brain / abnormalities*
  • Brain / pathology
  • Cerebral Ventricles / pathology
  • Child
  • Child, Preschool
  • Corpus Callosum / pathology
  • Dilatation, Pathologic
  • Fetal Alcohol Spectrum Disorders / pathology
  • Gigantism / pathology
  • Hereditary Sensory and Motor Neuropathy / pathology
  • Humans
  • Infant
  • Intellectual Disability / pathology*
  • Magnetic Resonance Imaging*
  • Noonan Syndrome / pathology
  • Oculocerebrorenal Syndrome / pathology
  • Syndrome