Clear cell adenocarcinoma arising from endometriosis in abdominal wall cesarean section scar: a case report and review of the literature

J Cutan Pathol. 2012 Nov;39(11):1035-41. doi: 10.1111/j.1600-0560.2012.01982.x. Epub 2012 Aug 11.


Malignancy arising in association with endometriosis is a rare but well-documented phenomenon that was first described in the literature as early as 1925. Cutaneous endometriosis with subsequent malignant transformation is even more uncommon, and high clinical suspicion is required for diagnosis. The clinical differential diagnosis of these lesions includes a wide variety of entities, ranging from benign cysts to malignancies such as melanoma. We report a case of clear cell adenocarcinoma arising from endometriosis in a cesarean section scar in a 47-year-old woman, and we complete a review of the literature regarding this unusual entity.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma, Clear Cell* / etiology
  • Adenocarcinoma, Clear Cell* / pathology
  • Cesarean Section*
  • Cicatrix* / complications
  • Cicatrix* / pathology
  • Endometriosis* / complications
  • Endometriosis* / pathology
  • Female
  • Humans
  • Middle Aged
  • Postoperative Complications / pathology*
  • Skin Neoplasms* / etiology
  • Skin Neoplasms* / pathology