Chapter 3: Cohort life tables by smoking status, removing lung cancer as a cause of death

Risk Anal. 2012 Jul;32 Suppl 1(Suppl 1):S25-38. doi: 10.1111/j.1539-6924.2011.01662.x.

Abstract

The purpose of this study was to develop life tables by smoking status removing lung cancer as a cause of death. These life tables are inputs to studies that compare the effectiveness of lung cancer treatments or interventions, and provide a way to quantify time until death from causes other than lung cancer. The study combined actuarial and statistical smoothing methods, as well as data from multiple sources, to develop separate life tables by smoking status, birth cohort, by single year of age, and by sex. For current smokers, separate life tables by smoking quintiles were developed based on the average number of cigarettes smoked per day by birth cohort. The end product is the creation of six non-lung-cancer life tables for males and six tables for females: five current smoker quintiles and one for never smokers. Tables for former smokers are linear combinations of the appropriate table based on the current smoker quintile before quitting smoking and the never smoker probabilities, plus added covariates for the smoking quit age and time since quitting.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Calibration
  • Cause of Death
  • Cohort Studies
  • Female
  • Humans
  • Life Tables
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / mortality*
  • Male
  • Models, Statistical
  • Risk
  • Risk Factors
  • Sex Factors
  • Smoking / adverse effects*
  • Smoking / epidemiology*
  • Smoking Cessation