Acute increases in plasma mammalian target of rapamycin, glycogen synthase kinase-3β, and eukaryotic elongation factor 2 phosphorylation after ketamine treatment in three depressed patients

Biol Psychiatry. 2013 Jun 15;73(12):e35-6. doi: 10.1016/j.biopsych.2012.07.022. Epub 2012 Aug 9.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antidepressive Agents / therapeutic use*
  • Depression / blood
  • Depression / drug therapy
  • Eukaryotic Initiation Factor-2 / blood*
  • Glycogen Synthase Kinase 3 / blood*
  • Glycogen Synthase Kinase 3 beta
  • Humans
  • Ketamine / therapeutic use*
  • Male
  • Phosphorylation / drug effects
  • Sirolimus / blood*
  • Time Factors
  • Young Adult

Substances

  • Antidepressive Agents
  • Eukaryotic Initiation Factor-2
  • Ketamine
  • GSK3B protein, human
  • Glycogen Synthase Kinase 3 beta
  • Glycogen Synthase Kinase 3
  • Sirolimus