Consuming polydextrose in a mid-morning snack increases acute satiety measurements and reduces subsequent energy intake at lunch in healthy human subjects

Appetite. 2012 Dec;59(3):706-12. doi: 10.1016/j.appet.2012.08.004. Epub 2012 Aug 10.


Polydextrose (Litesse®, DuPont) is a polysaccharide that is partially fermented in the colon. Evidence suggests that polydextrose increases satiety when consumed over several weeks; however studies assessing its acute effects on satiety are lacking. This study therefore aimed to assess the impact of different doses of polydextrose on satiety and energy intake at subsequent meals during a test day. Three yogurt-based drinks containing different amounts of polydextrose (0, 6.25 and 12.5g) were tested using a randomised, single-blinded, placebo controlled, cross-over design. Thirty-four healthy male and female volunteers were provided with a standard breakfast, then consumed the test product mid-morning, 90min before an ad libitum lunch, which was followed by an ad libitum dinner. Visual analogue scales were used to measure subjective ratings of appetite, liking and discomfort. Consuming 6.25 and 12.5g polydextrose increased satiety and decreased appetite compared to control immediately after consumption. A reduction in energy intake (218.8kJ) at lunchtime was observed for 12.5g polydextrose. This reduction in energy intake was not compensated for at dinner. This study suggests that polydextrose may aid in increasing satiety feelings post consumption and also reduce energy intake as a result.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Appetite / drug effects*
  • Cross-Over Studies
  • Diet*
  • Dietary Carbohydrates / pharmacology
  • Energy Intake / drug effects*
  • Feeding Behavior / drug effects*
  • Female
  • Fermentation
  • Glucans / pharmacology*
  • Humans
  • Lunch
  • Male
  • Reference Values
  • Satiation / drug effects*
  • Satiety Response / drug effects*
  • Single-Blind Method
  • Snacks
  • Yogurt


  • Dietary Carbohydrates
  • Glucans
  • polydextrose