Ability of endophytic filamentous fungi associated with Cinchona ledgeriana to produce Cinchona alkaloids

Shoji Maehara; Partomuan Simanjuntak; Yoshihide Maetani; Chinami Kitamura; Kazuyoshi Ohashi; Hirotaka Shibuya

doi:10.1007/s11418-012-0701-8

Ability of endophytic filamentous fungi associated with Cinchona ledgeriana to produce Cinchona alkaloids

J Nat Med. 2013 Apr;67(2):421-3. doi: 10.1007/s11418-012-0701-8. Epub 2012 Aug 11.

Authors

Shoji Maehara¹, Partomuan Simanjuntak, Yoshihide Maetani, Chinami Kitamura, Kazuyoshi Ohashi, Hirotaka Shibuya

Affiliation

¹ Fukuyama University, Sanzo, 1 Gakuen-cho, Fukuyama, Hiroshima, 729-0292, Japan.

PMID: 22886817
DOI: 10.1007/s11418-012-0701-8

Abstract

We have investigated the ability of endophytic filamentous fungi associated with Cinchona ledgeriana (Rubiaceae) to produce Cinchona alkaloids on potato dextrose agar medium and in a synthetic liquid medium. It was found that all twenty-one endophytic fungi produce Cinchona alkaloids, despite their genetic differences.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cinchona / microbiology*
Cinchona Alkaloids / metabolism*
Fungi / metabolism*
Fungi / physiology*
Molecular Structure

Substances

Cinchona Alkaloids