Abstract
To date, RNA interference remains the most powerful and promising tool for gene-targeted therapy. Several problems still have to be solved for its successful use in clinics. One of the main issues is the siRNA's efficient delivery. This review covers various types of nonviral siRNA delivery systems.
MeSH terms
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Aptamers, Nucleotide / chemistry
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Biocompatible Materials / chemistry
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Drug Delivery Systems / methods*
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Genetic Therapy*
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Humans
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Lipids / chemistry
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Lipopeptides / chemistry
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Liposomes / chemistry
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Nanoparticles / chemistry
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Polymers / chemistry
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RNA Interference*
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RNA, Small Interfering / chemistry*
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RNA, Small Interfering / genetics
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Static Electricity
Substances
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Aptamers, Nucleotide
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Biocompatible Materials
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Lipids
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Lipopeptides
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Liposomes
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Polymers
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RNA, Small Interfering