[Perioperative medication management]

Dtsch Med Wochenschr. 2012 Aug;137(34-35):e1-8. doi: 10.1055/s-0032-1305245. Epub 2012 Aug 14.
[Article in German]


The management of chronic medication in the perioperative phase represents as a serious challenge for the involved physicians. Especially patients with elevated ASA-scores frequently suffer from multiple co-morbidities which often need numerous medications. The probability of pharmacological interactions rises with the number of these medications. Moreover it must be taken into consideration that chronic medication potentially interferes with both intravenous and inhaled anesthetics and moreover, bleeding complications are more likely to occur in patients undergoing chronic pharmacotherapy. The aim of this article is to provide a summary of the existing evidence concerning perioperative medication in patients undergoing non-cardiac surgery. Several guidelines and advisories dealing with cardiovascular medication have been published during the last decade. The main scope of these publications was on beta-blockers and other cardiovascular medication. There is less evidence on not-cardiovascular medication as in most cases only case reports and expert opinions are published. Existing epidemiologic studies on this topic are rather heterogeneous.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adrenergic beta-Antagonists / administration & dosage
  • Adrenergic beta-Antagonists / adverse effects
  • Anesthesia, General*
  • Anesthetics / adverse effects*
  • Cardiovascular Agents / administration & dosage
  • Cardiovascular Agents / adverse effects
  • Chronic Disease / drug therapy*
  • Drug Interactions*
  • Drug Therapy, Combination
  • Evidence-Based Medicine
  • Health Status Indicators*
  • Humans
  • Long-Term Care*
  • Perioperative Care*


  • Adrenergic beta-Antagonists
  • Anesthetics
  • Cardiovascular Agents