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Case Reports
. 2012 Oct;50(10):3409-11.
doi: 10.1128/JCM.00802-12. Epub 2012 Aug 15.

Meningoencephalitis With Subdural Empyema Caused by Toxigenic Clostridium Perfringens Type A

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Case Reports

Meningoencephalitis With Subdural Empyema Caused by Toxigenic Clostridium Perfringens Type A

Michael Hugelshofer et al. J Clin Microbiol. .
Free PMC article

Abstract

We report a clinical case of meningoencephalitis with subdural empyema in an immunocompromised farmer caused by toxigenic Clostridium perfringens type A, which was identified by 16S RNA gene analysis of cerebrospinal fluid and subdural empyema. In immunocompromised patients, C. perfringens should be considered a potential pathogen of sepsis.

Figures

Fig 1
Fig 1
(a) Native CT scan of the patient's head at admission to our institution. Arrows mark hypodense parieto-occipital lesion. Extensive brain swelling of the right hemisphere with elapsed sulci is shown. (b) Native CT scan of the patient's head before transfer to the communal hospital. Arrows mark a residual hypodense parieto-occipital lesion. A relaxed right hemisphere with pronounced sulci is shown. Arrowheads mark residual blood of the left frontal hemorrhage. (c) Coronary native CT scan of patient's head before surgical intervention. Arrows mark a hypodense right frontal lesion. Extensive brain swelling of the right hemisphere with elapsed sulci is shown. (d) Coronary native CT scan of the patient's head after surgical intervention. Virtually complete evacuation of the right frontal subdural lesion is shown. An arrowhead marks the intraventricular catheter. Arrows mark the small IVD-associated hemorrhage.

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