Imaging of scleroma in the head and neck

Br J Radiol. 2012 Dec;85(1020):1551-5. doi: 10.1259/bjr/15189057. Epub 2012 Aug 16.


We review the appearance of scleroma in the head and neck on imaging. Scleroma is a chronic granulomatous disease that primarily affects the nasal cavity, but the pharynx and larynx may also be involved. On imaging, nasal scleroma appears as bilateral or unilateral expanded homogeneous nasal masses that may exhibit hyperintense signal on T(1) weighted images. Pharyngeal scleroma commonly narrows the pharyngeal lumen and may involve the soft and hard palate. Imaging is essential to detect the extent of subglottic stenosis in patients with laryngeal scleroma. Rarely, scleroma may involve the orbit or the middle ear. Imaging is essential for the early diagnosis of scleroma and for differentiating it from other granulomatous and neoplastic lesions. Also, imaging is important for treatment planning and follow-up of patients after therapy.

Publication types

  • Review

MeSH terms

  • Bone Diseases / diagnosis
  • Bone Diseases / etiology
  • Diagnosis, Differential
  • Ear Diseases / diagnosis
  • Ear Diseases / etiology
  • Ear, Middle
  • Early Diagnosis
  • Head
  • Humans
  • Laryngeal Diseases / diagnosis
  • Laryngeal Diseases / etiology
  • Lymphatic Diseases / diagnosis
  • Lymphatic Diseases / etiology
  • Mouth Diseases / diagnosis
  • Mouth Diseases / etiology
  • Neck
  • Nose Diseases / diagnosis
  • Nose Diseases / etiology
  • Orbital Diseases / diagnosis
  • Orbital Diseases / etiology
  • Pharyngeal Diseases / diagnosis
  • Pharyngeal Diseases / etiology
  • Rhinoscleroma / diagnosis*
  • Rhinoscleroma / etiology
  • Skull Base