Frequency and clinical manifestations of post-poliomyelitis syndrome in a Brazilian tertiary care center

Arq Neuropsiquiatr. 2012 Aug;70(8):571-3. doi: 10.1590/s0004-282x2012000800002.


Objective: To determine the frequency and clinical manifestations of patients with post-poliomyelitis syndrome (PPS) in a Brazilian division of neuromuscular disorders.

Methods: A total of 167 patients with prior history of paralytic poliomyelitis was investigated for PPS, based on international diagnostic criteria. Other variables analyzed were: gender, race, age at poliomyelitis infection, age at PPS onset, and PPS symptoms.

Results: One hundred and twenty-nine patients presented PPS, corresponding to 77.2% of the studied population. 62.8% were women and 37.2% were men. Mean age of patients with PPS at onset of PPS symptoms was 39.9±9.69 years. Their main clinical manifestations were: new weakness in the previously affected limbs (69%) and in the apparently not affected limbs (31%); joint pain (79.8%); fatigue (77.5%); muscle pain (76%); and cold intolerance (69.8%).

Conclusions: Most patients of our sample presented PPS. In Brazil, PPS frequency and clinical features are quite similar to those of other countries.

MeSH terms

  • Adult
  • Brazil / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscle Weakness / diagnosis
  • Postpoliomyelitis Syndrome / diagnosis
  • Postpoliomyelitis Syndrome / epidemiology*
  • Prevalence
  • Tertiary Care Centers / statistics & numerical data