MPK11-a fourth elicitor-responsive mitogen-activated protein kinase in Arabidopsis thaliana

Plant Signal Behav. 2012 Sep 1;7(9):1203-5. doi: 10.4161/psb.21323. Epub 2012 Aug 17.

Abstract

Recognition of pathogen attack or elicitation with pathogen-associated molecular patterns (PAMPs) leads to defense signaling that includes activation of the three mitogen-activated protein kinases (MPKs), MPK3, MPK4 and MPK6 in Arabidopsis. Recently, we demonstrated the activation of a fourth MPK, MPK11, after treatment with flg22, a 22 amino acid PAMP derived from bacterial flagellin. Here, we extended the study by examining elicitation with two other PAMPs, elf18 (derived from bacterial elongation factor EF-Tu) and ch8 (N-acetylchitooctaose derived from fungal chitin). Both PAMPs led to rapid MPK11 transcript accumulation and increased MPK11 kinase activity, suggesting that multiple PAMPs (or stresses) can activate MPK11. However, probably due to functional redundancies, bacteria-induced phytoalexin accumulation does not absolutely require MPK11.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / drug effects
  • Arabidopsis / metabolism*
  • Arabidopsis / microbiology
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism*
  • Bacterial Proteins / pharmacology*
  • Flagellin / pharmacology
  • Fungal Proteins / pharmacology*
  • Mitogen-Activated Protein Kinases / genetics
  • Mitogen-Activated Protein Kinases / metabolism*
  • Oligosaccharides / pharmacology
  • Peptide Elongation Factor Tu / pharmacology
  • Plant Diseases / genetics
  • Plant Diseases / microbiology*
  • Plant Immunity* / drug effects
  • Plant Immunity* / genetics
  • Sesquiterpenes / metabolism*
  • Signal Transduction
  • Transcription, Genetic / drug effects

Substances

  • Arabidopsis Proteins
  • Bacterial Proteins
  • Fungal Proteins
  • Oligosaccharides
  • Sesquiterpenes
  • Flagellin
  • N-acetylchitooctaose
  • phytoalexins
  • MPK11 protein, Arabidopsis
  • Mitogen-Activated Protein Kinases
  • Peptide Elongation Factor Tu