Clostridium celerecrescens, often misidentified as "Clostridium clostridioforme group," is involved in rare human infection cases

Diagn Microbiol Infect Dis. 2012 Nov;74(3):299-302. doi: 10.1016/j.diagmicrobio.2012.06.024. Epub 2012 Aug 15.

Abstract

Misidentification of rare Clostridium species often originated from the environment as clinically relevant species is problematic. A strain isolated from a traumatic leg wound first identified as C. clostridioforme was finally identified as the rare Clostridium celerecrescens. Two similar misidentifications are reported in the literature. In order to help the phenotypic differentiation of C. celerecrescens from the close species of the "C. clostridioforme group", an identification table and differential susceptibilities to 4 selected antibiotics are proposed. Once a clinical isolate is referred to this group, identification should be definitively confirmed by unambiguous methods such as 16s rDNA sequencing.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Typing Techniques
  • Clostridium / classification
  • Clostridium / genetics
  • Clostridium / isolation & purification*
  • Clostridium / pathogenicity*
  • Clostridium Infections / diagnosis*
  • Clostridium Infections / microbiology*
  • Clostridium Infections / pathology
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Wound Infection / microbiology*
  • Wound Infection / pathology*
  • Wounds and Injuries / complications
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S

Associated data

  • GENBANK/JQ246092