[Severe liver involvement by Capillaria hepatica]

Monatsschr Kinderheilkd. 1990 Nov;138(11):767-71.
[Article in German]

Abstract

Human hepatic capillariasis is a rare disease, which predominantly affects children aged 1 to 4 years and has a poor prognosis in extensive infections. This is the first case observed in Germany. The main symptoms are those of severe parasitosis: persistent high fever, hepatomegaly, and excessive hypereosinophilia. Diagnosis is confirmed by the finding of intracellular typical eggs in liver biopsy. There is a lack of established therapy; our 18 months old girl developed liver fibrosis. She survived under a prolonged treatment with high doses of Thiabendazole and two single doses of Ivermectine. Decortin was given to inhibit further granulomatous processes in the liver.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Capillaria* / ultrastructure
  • Diagnosis, Differential
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Female
  • Humans
  • Infant
  • Ivermectin / administration & dosage
  • Liver / pathology
  • Liver Diseases, Parasitic / diagnosis*
  • Liver Diseases, Parasitic / drug therapy
  • Liver Diseases, Parasitic / pathology
  • Nematode Infections / diagnosis*
  • Nematode Infections / drug therapy
  • Nematode Infections / pathology
  • Thiabendazole / administration & dosage

Substances

  • Ivermectin
  • Thiabendazole