Presentation and management of an acute caffeine overdose

Pediatr Emerg Care. 1990 Dec;6(4):296-8. doi: 10.1097/00006565-199012000-00012.


A one-year-old white female ingested approximately two to three grams of caffeine (200-300 mg/kg). The patient survived the ingestion with a maximum caffeine concentration of 385 micrograms/ml four hours postingestion. The child developed ventricular arrhythmias, seizures, metabolic disturbances, and severe pulmonary edema. She survived without apparent long-term sequelae despite having reached a serum caffeine concentration that is the second highest reported level in a survivor.

Publication types

  • Case Reports

MeSH terms

  • Caffeine / poisoning*
  • Drug Overdose / therapy
  • Female
  • Humans
  • Infant
  • Respiratory Distress Syndrome / chemically induced
  • Seizures / chemically induced
  • Tachycardia / chemically induced


  • Caffeine