Abstract
A small library of novel germacrenes was generated using a combination of two plant enzymes, germacrene A synthase, and D synthase and modified farnesyl diphosphate (FDP) analogues. This chemoenzymatic approach allows the preparation of potentially valuable volatiles for biological studies.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkyl and Aryl Transferases / chemistry
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Alkyl and Aryl Transferases / metabolism*
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Molecular Structure
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Sesquiterpenes, Germacrane / biosynthesis*
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Sesquiterpenes, Germacrane / chemistry
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Small Molecule Libraries / chemistry
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Small Molecule Libraries / metabolism*
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Solidago / enzymology
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Stereoisomerism
Substances
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Sesquiterpenes, Germacrane
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Small Molecule Libraries
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germacrene A
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Alkyl and Aryl Transferases
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germacrene A synthase, Solidago canadensis
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germacrene D synthase
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germacrene D