Programmed genome rearrangements: in lampreys, all cells are not equal

Marie Sémon; Michael Schubert; Vincent Laudet

doi:10.1016/j.cub.2012.06.022

Programmed genome rearrangements: in lampreys, all cells are not equal

Curr Biol. 2012 Aug 21;22(16):R641-3. doi: 10.1016/j.cub.2012.06.022.

Authors

Marie Sémon¹, Michael Schubert, Vincent Laudet

Affiliation

¹ Institut de Génomique Fonctionnelle de Lyon (UMR 5242 du CNRS, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1), Université de Lyon, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.

PMID: 22917513
DOI: 10.1016/j.cub.2012.06.022

Abstract

How can organisms silence deleterious gene loci? A recent study has shed light on a very brute mechanism in a jawless vertebrate: the irreversible deletion of massive chunks of genomic DNA.

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MeSH terms

Animals
Female
Gene Deletion*
Gene Rearrangement*
Genome*
Germ Cells / metabolism*
Lampreys / genetics*
Male