Enantioselective aza-Henry reactions of cyclic α-carbonyl ketimines under bifunctional catalysis

Chem Commun (Camb). 2012 Oct 9;48(78):9759-61. doi: 10.1039/c2cc34053d.

Abstract

The aza-Henry reaction of nitroalkanes with the C=N group of 2-aryl-3H-indol-3-ones catalyzed by thiourea-chincona derivatives takes place with good yield and high ee's.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkanes / chemical synthesis*
  • Alkanes / chemistry
  • Catalysis
  • Imines / chemistry*
  • Indoles / chemistry*
  • Molecular Structure
  • Nitriles / chemistry*
  • Nitro Compounds / chemical synthesis*
  • Nitro Compounds / chemistry
  • Stereoisomerism

Substances

  • Alkanes
  • Imines
  • Indoles
  • Nitriles
  • Nitro Compounds
  • ketimine