[Could gosereline acetate induce autoimmune-like hepatitis?]

Prog Urol. 2012 Sep;22(10):610-2. doi: 10.1016/j.purol.2012.06.010. Epub 2012 Jul 24.
[Article in French]

Abstract

We report a case of acute icteric hepatitis attributed to goserelin acetate, occurred during prostate cancer treatment. Gosereline acetate could induce acute hepatitis, which characteristics are close to autoimmune hepatitis type I and may require hepatic monitoring.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Hormonal / adverse effects*
  • Autoimmune Diseases / chemically induced*
  • Chemical and Drug Induced Liver Injury / etiology*
  • Chemical and Drug Induced Liver Injury / immunology*
  • Goserelin / adverse effects*
  • Humans
  • Male
  • Middle Aged

Substances

  • Antineoplastic Agents, Hormonal
  • Goserelin