HiTC: exploration of high-throughput 'C' experiments

Bioinformatics. 2012 Nov 1;28(21):2843-4. doi: 10.1093/bioinformatics/bts521. Epub 2012 Aug 24.


Summary: The R/Bioconductor package HiTC facilitates the exploration of high-throughput 3C-based data. It allows users to import and export 'C' data, to transform, normalize, annotate and visualize interaction maps. The package operates within the Bioconductor framework and thus offers new opportunities for future development in this field.

Availability and implementation: The R package HiTC is available from the Bioconductor website. A detailed vignette provides additional documentation and help for using the package.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Mapping / instrumentation
  • Chromosome Mapping / methods*
  • Chromosomes, Human, Pair 14 / chemistry
  • Chromosomes, Human, Pair 14 / genetics
  • Data Display
  • Humans
  • Mice
  • Molecular Conformation
  • Restriction Mapping / instrumentation
  • Restriction Mapping / methods*
  • Software*