Laugier-Hunziker syndrome
- PMID: 22923898
- PMCID: PMC3424942
- DOI: 10.4103/0973-029X.99079
Laugier-Hunziker syndrome
Abstract
Laugier-Hunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. They appear as macular lesions less than 5 mm in diameter. Laugier-Hunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential. Therefore, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management. Prompt clinical recognition also averts the need for excessive and invasive procedures and treatments. In India, the reported cases of this syndrome are very few. We provide a review of literature on Laugier-Hunziker syndrome with its differential diagnosis.
Keywords: Differential diagnosis; Laugier–Hunziker syndrome; mucocutaneous pigmentation; oral pigments.
Conflict of interest statement
Similar articles
-
Clinical and histopathological differential diagnosis of Laugier-Hunziker syndrome: An extremely rare case with unusual extensive oral hyperpigmentation.Clin Case Rep. 2020 Nov 16;9(1):309-313. doi: 10.1002/ccr3.3522. eCollection 2021 Jan. Clin Case Rep. 2020. PMID: 33489178 Free PMC article.
-
Laugier-Hunziker Syndrome in an 8-Year-Old Boy with Scleral Melanocytosis, Lingual Pigmentation, Labial Pigmentation, and Melanonychia Striata.Case Rep Pediatr. 2020 Mar 17;2020:8267805. doi: 10.1155/2020/8267805. eCollection 2020. Case Rep Pediatr. 2020. PMID: 32257493 Free PMC article.
-
Laugier-Hunziker syndrome: A case report and review of the literature.Dermatol Online J. 2010 Dec 15;16(12):9. Dermatol Online J. 2010. PMID: 21199635 Review.
-
Laugier-hunziker syndrome in a patient with pancreatic cancer.Case Rep Dermatol. 2012 May;4(2):174-6. doi: 10.1159/000342070. Epub 2012 Aug 16. Case Rep Dermatol. 2012. PMID: 22949900 Free PMC article.
-
Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome.World J Clin Cases. 2018 Sep 26;6(10):322-334. doi: 10.12998/wjcc.v6.i10.322. World J Clin Cases. 2018. PMID: 30283795 Free PMC article. Review.
Cited by
-
Isolated Palmoplantar Lentiginosis.Clin Cosmet Investig Dermatol. 2023 Jun 27;16:1653-1657. doi: 10.2147/CCID.S415686. eCollection 2023. Clin Cosmet Investig Dermatol. 2023. PMID: 37396712 Free PMC article.
-
Peutz-Jeghers Syndrome and the Role of Imaging: Pathophysiology, Diagnosis, and Associated Cancers.Cancers (Basel). 2021 Oct 13;13(20):5121. doi: 10.3390/cancers13205121. Cancers (Basel). 2021. PMID: 34680270 Free PMC article. Review.
-
[Laugier-Hunziker syndrome : A rare differential diagnosis of mucocutaneous hyperpigmentation].Hautarzt. 2022 Apr;73(4):298-302. doi: 10.1007/s00105-021-04845-x. Epub 2021 Jun 25. Hautarzt. 2022. PMID: 34170334 Free PMC article. German.
-
Clinical and histopathological differential diagnosis of Laugier-Hunziker syndrome: An extremely rare case with unusual extensive oral hyperpigmentation.Clin Case Rep. 2020 Nov 16;9(1):309-313. doi: 10.1002/ccr3.3522. eCollection 2021 Jan. Clin Case Rep. 2020. PMID: 33489178 Free PMC article.
-
Laugier-Hunziker Syndrome in an 8-Year-Old Boy with Scleral Melanocytosis, Lingual Pigmentation, Labial Pigmentation, and Melanonychia Striata.Case Rep Pediatr. 2020 Mar 17;2020:8267805. doi: 10.1155/2020/8267805. eCollection 2020. Case Rep Pediatr. 2020. PMID: 32257493 Free PMC article.
References
-
- Siponen M, Salo T. Idiopathic lenticular mucocutaneous pigmentation (Laugier-Hunziker syndrome): A report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;96:288–92. - PubMed
-
- Lamey PJ, Nolan A, Thomson E, Lewis MA, Rademaker M. Oral presentation of the Laugier-Hunziker syndrome. Br Dent J. 1991;171:59–60. - PubMed
-
- Baran R, Barrière H. Longitudinal melanonychia with spreading pigmentation in Laugier-Hunziker syndrome: A report of two cases. Br J Dermatol. 1986;115:707–10. - PubMed
-
- Pereira PM, Rodrigues CA, Lima LL, Reyes SA, Mariano AV. Do you know this syndrome? An Bras Dermatol. 2010;85:751–3. - PubMed
-
- Jabbari A, Gonzalez ME, Franks AG, Jr, Sanchez M. Laugier Hunziker syndrome. Dermatol Online J. 2010;16:23. - PubMed
