Multiple synchronous outbreaks of Puumala virus, Germany, 2010

Emerg Infect Dis. 2012 Sep;18(9):1461-4. doi: 10.3201/eid1809.111447.


To investigate 2,017 cases of hantavirus disease in Germany, we compared 38 new patient-derived Puumala virus RNA sequences identified in 2010 with bank vole-derived small segment RNA sequences. The epidemic process was driven by outbreaks of 6 Puumala virus clades comprising strains of human and vole origin. Each clade corresponded to a different outbreak region.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Outbreaks*
  • Germany / epidemiology
  • Hemorrhagic Fever with Renal Syndrome / epidemiology*
  • Humans
  • Phylogeny
  • Puumala virus / classification
  • Puumala virus / genetics*
  • RNA, Viral


  • RNA, Viral