Middle cerebral artery Doppler and hemoglobin changes immediately following fetal transfusion

J Matern Fetal Neonatal Med. 2013 Jan;26(2):155-7. doi: 10.3109/14767058.2012.725114. Epub 2012 Sep 24.


Objective: To determine the relationship between the change in middle cerebral artery peak systolic velocity (MCA-PSV) and the change in fetal Hemoglobin (Hb) immediately following intrauterine transfusion (IUT).

Materials and methods: Study data included all IUTs performed for suspected fetal anemia from 2007-2011.

Results: Sixty-eight IUTs were performed for 23 pregnancies, demonstrating a statistically significant MCA-PSV decrease for up to four IUTs. Significant correlations between changes in Hb levels and MCA-PSV were not detected.

Conclusion: MCA-PSV values were highly variable in the immediate post-operative period and did not correlate with the Hb change.

MeSH terms

  • Anemia / blood
  • Anemia / diagnostic imaging*
  • Anemia / therapy
  • Blood Flow Velocity
  • Blood Transfusion, Intrauterine*
  • Female
  • Fetal Diseases / blood
  • Fetal Diseases / diagnostic imaging*
  • Fetal Diseases / therapy
  • Fetal Hemoglobin / metabolism*
  • Humans
  • Middle Cerebral Artery / physiology*
  • Pregnancy
  • Retrospective Studies
  • Treatment Outcome
  • Ultrasonography, Doppler, Color
  • Ultrasonography, Prenatal


  • Fetal Hemoglobin