The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping

Mamm Genome. 2012 Oct;23(9-10):632-40. doi: 10.1007/s00335-012-9427-x. Epub 2012 Sep 1.


Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.

MeSH terms

  • Animals
  • Internationality
  • Mice
  • Mice, Mutant Strains
  • Phenotype*