The integrative approach to health information in general and the development of pHealth systems in particular, require an integrated approach of formally modeled system architectures. Detailed Clinical Models (DCM) is one of the most promising modeling efforts for clinical concept representation in EHR system architectures. Although the feasibility of DCM modeling methodology has been demonstrated through examples, there is no formal, generic and automatic modeling transformation technique to ensure a semantic lossless transformation of clinical concepts expressed in DCM to either clinical concept representations based on ISO 13606/openEHR Archetypes or HL7 Templates. The objective of this paper is to propose a generic model transformation method and tooling for transforming DCM Clinical Concepts into ISO/EN 13606/openEHR Archetypes or HL7 Template models. The automation of the transformation process is supported by Model Driven-Development (MDD) transformation mechanisms and tools. The availability of processes, techniques and tooling for automatic DCM transformation would enable the development of intelligent, adaptive information systems as demanded for pHealth solutions.