Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1990 Jan;93(1):148-52.
doi: 10.1093/ajcp/93.1.148.

Giant Cell Myocarditis Associated With Silicone. An Unusual Case of Biomaterials Pathology Discovered at Autopsy Using X-ray Energy Spectroscopic Techniques

Affiliations
Case Reports

Giant Cell Myocarditis Associated With Silicone. An Unusual Case of Biomaterials Pathology Discovered at Autopsy Using X-ray Energy Spectroscopic Techniques

N Kossovsky et al. Am J Clin Pathol. .

Abstract

Silicones, used extensively in the fabrication of medical devices because they were presumed inert and biocompatible, are now well-recognized inducers of localized granulomatous inflammation. Silicones less commonly are also associated with more complex clinico-pathologic entities. In this communication, the authors present a case of a patient on chronic hemodialysis involving tubing probably fabricated from silicone rubber who died from a giant cell myocarditis associated with silicone rubber. This case is presented to expand the interpretive paradigm of human pathology and underscores the need for pathologists to consider medical-device associated phenomena in the differential diagnosis of clinical specimens.

Similar articles

See all similar articles

Cited by 3 articles

Publication types

Substances

LinkOut - more resources

Feedback