Comparative genomics: a revolutionary tool for wine yeast strain development

Curr Opin Biotechnol. 2013 Apr;24(2):192-9. doi: 10.1016/j.copbio.2012.08.006. Epub 2012 Sep 1.


The application of Next Generation sequencing to comparative genomics is enabling in-depth characterization of genetic variation between wine yeast strains used in fermentation starter cultures. Knowledge from this work will be harnessed in strain development programs. As a result, winemakers will soon have at their disposal novel, improved yeast starter cultures displaying increased reliability and providing a means of tailoring wine sensory characteristics for new and ever-changing markets.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Fermentation
  • Genetic Markers
  • Genetic Variation / genetics
  • Genome, Fungal / genetics*
  • Genomics*
  • Multigene Family / genetics
  • Phylogeny
  • Reproducibility of Results
  • Saccharomyces cerevisiae / classification*
  • Saccharomyces cerevisiae / genetics*
  • Wine / microbiology*


  • Genetic Markers