Dapsone 5% gel: a new option in topical therapy for acne

Skin Therapy Lett. 2012 Sep;17(8):1-3.


Dapsone 5% gel for the topical treatment for acne vulgaris was recently introduced in Canada. It represents the first new anti-acne agent to gain North American regulatory approval in the past decade. Dapsone's utility is attributable to its anti-inflammatory and antimicrobial properties that improve both inflammatory and non-inflammatory acne, with more prominent effects occurring in inflammatory lesions. Short- and long-term safety and efficacy have been demonstrated. Especially for patients exhibiting sensitivities or intolerance to conventional anti-acne agents, topical dapsone is a novel addition to the treatment armamentarium.

MeSH terms

  • Acne Vulgaris / drug therapy*
  • Administration, Topical
  • Anti-Infective Agents / administration & dosage*
  • Anti-Inflammatory Agents / administration & dosage*
  • Dapsone / administration & dosage*
  • Gels / administration & dosage
  • Humans
  • Randomized Controlled Trials as Topic
  • Treatment Outcome


  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Gels
  • Dapsone