Copper-catalyzed electrophilic amination of alkenylzirconocenes with O-benzoylhydroxylamines: an efficient method for synthesis of enamines

Org Lett. 2012 Sep 21;14(18):4750-3. doi: 10.1021/ol302004t. Epub 2012 Sep 6.

Abstract

Copper-catalyzed electrophilic amination of alkenylzirconocenes is accomplished under mild reaction conditions. The reaction tolerates a wide range of functional groups and can be used to prepare some hindered enamines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemical synthesis*
  • Alkenes / chemistry
  • Amination
  • Amines / chemical synthesis*
  • Amines / chemistry
  • Catalysis
  • Combinatorial Chemistry Techniques
  • Copper / chemistry*
  • Molecular Structure

Substances

  • Alkenes
  • Amines
  • Copper