Cardiac resynchronization therapy as rescue therapy in end-stage heart failure: illustration by three-dimensional speckle tracking strain echocardiography

Echocardiography. 2012 Nov;29(10):E264-6. doi: 10.1111/j.1540-8175.2012.01814.x. Epub 2012 Sep 7.


We report the case of a 73-year-old man admitted for refractory heart failure following implantation of a dual-chamber pacemaker. Three-dimensional (3D) echocardiography with speckle tracking area strain identified severe left ventricular (LV) dysfunction and LV dyssynchrony following right ventricular pacing. As the patient's clinical condition rapidly worsened despite optimal medical treatment, a cardiac resynchronization therapy (CRT) pacemaker was successfully implanted as rescue therapy. Symptoms rapidly regressed and echocardiographic assessment following CRT demonstrated an immediate improvement in LV systolic function, confirmed at 9-month follow-up with evidence of reverse remodeling. New imaging technologies such as 3D echocardiography with speckle tracking area strain may help to identify and follow up patients who will benefit from CRT as rescue therapy.

Keywords: cardiac pacing; cardiogenic shock; heart failure; left ventricular remodeling; strain; three-dimensional transthoracic echocardiography.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiac Resynchronization Therapy / methods*
  • Echocardiography, Three-Dimensional / methods*
  • Follow-Up Studies
  • Heart Failure / diagnostic imaging
  • Heart Failure / physiopathology
  • Heart Failure / therapy*
  • Humans
  • Male
  • Ventricular Remodeling / physiology*