Deterministic or stochastic choices in retinal neuron specification

Neuron. 2012 Sep 6;75(5):739-42. doi: 10.1016/j.neuron.2012.08.008.


There are two views on vertebrate retinogenesis: a deterministic model dependent on fixed lineages and a stochastic model in which choices of division modes and cell fates cannot be predicted. In this issue of Neuron, He et al. (2012) address this question in zebrafish using live imaging and mathematical modeling.

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